Flight
South Carolina has many airports, but the Charleston (CHS) International Airport is definitely the easiest for domestic flights and is only a short car ride from all hotel and rental suggestions.
Hotel
Hotel(s) offering your special group rate: Grant-Smalls Wedding Residence Inn Charleston Mt. Pleasant for 150 USD - 240 USD per night full king suite or two bedroom suite, includes breakfast Courtyard Charleston Mt. Pleasant for 135 USD per night - standard room with one king or two queen beds