Flight
From here you can take a train, taxi or rent a car.
Train
You can take a train from Rome Termini or Rome Tiburtina to Montepulciano (town next to Monticchiello) or Chiusi/Chianciano Terme Station. From there it's a ~10-20 minute taxi ride depending on your selected accommodation.
Rental Car
You can rent a car from any of the airports by booking via their website.
Hotel
House Or Rental
Can accommodate 2-4 people
House Or Rental
Can accommodate 4 people
House Or Rental
Can accommodate 5 people
House Or Rental
Can accommodate 6 people