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OAX
No, no and no. You can get from the airport to your hotel in the historic district by taxi. After that everything is walkable. Bring comfortable shoes. The streets are cobblestone.
Civilizations in this area date to 1500 B.C. starting with the Olmecs, then Zapotecs and Mixtecs. Most of this timeline predates the Aztecs. https://www.ancient-origins.net/ancient-places-americas/monte-alban-0012219
If you arrive Thursday, take whatever time you have after checking in your hotel to wander the historic district. On Friday we encourage you to join the trip to Monte Alban and Friday evening is the Rehearsal Dinner to which all are invited. Sleep in on Saturday and save your energy for the wedding reception. Spend the day seeing the sights and markets of historic Oaxaca. The ceremony starts at 4:00 at the Quinta Real hotel. Sunday is your day to relax and recoup and recover if you've been up all night. However, if you saved some energy you might want to check out a palenque (Mezcal distillery) or go to a tasting.
Tequila is a kind of mezcal like bourbon is a kind of whiskey.
5,102 feet which is mile high, just like Denver, so hydrate with water and not mezcal the first 24 hours.
According to Zach Rabinor, CEO of Journey Mexico, Oaxaca's rising popularity is due to its "exquisite architecture, living indigenous culture, spectacular Zapotec and Mixtec archaeological sites, to-die-for cuisine and some of the most exceptional artisans in all of Mexico."