Flight
Book your flight into the New Orleans airport (MSY). Most downtown hotels have shuttles from the airport. You shouldn't need a rental car unless you plan to tour areas outside of the uptown/downtown area. New Orleans has a street car that can take you all over the downtown and into the uptown St. Charles and Audubon Park area
Hotel
This hotel is in the heart of downtown on Canal Street. It is within walking distance to Bourbon Street, Jackson Square and across the street from the Streetcar line that takes you into the Uptown St. Charles street area. It is also near some awesome restaurants including many Brennan's restaurants including Palace Cafe, Mr. B's, and Brennan's; as well as Acme Oyster House, the famous Mother's, Galatoire's and Andrea's. There is onsite valet parking for drivers.
Hotel
For all you party people, this hotel is located on Bourbon Street. It is closer to Canal Street and the Bourbon House and Red Fish restaurants. Make sure to check out Cat's Meow and grab a Hand Grenade drink while you're at it. Please remember to stay on Bourbon and other well-lit streets and avoid walking down side streets at night.
Hotel
This hotel is located between Poydras and Canal Street across from Harrah's casino. It is within walking distance of the Red car on the river and Aquarium. You can walk to Fulton Alley which has many fun things including an indoor bowling alley. Also nearby, for you beer lovers, is Gordon Biersch with beers from around the world