Hotel
There are a number of historic and cozy bed & breakfasts in Beaufort for your consideration: - Ann Street Inn - The Cedars Inn - Inn On Turner - Langdon House - Pecan Tree Inn
Flight
In general, Raleigh-Durham International Airport will likely be the best airport to fly into. However, these regional airports may be worth considering: Wilmington International Airport in Wilmington, NC and Coastal Regional Airport in New Bern, NC.