If you're looking to make a vacation out of the wedding, South Lake Tahoe is our favorite place to "visit". That's in quotations because we practically lived there part-time in the winters.
If you're looking for a central place to stay in San Francisco, this is it! It's conveniently located next door to the best arcade bar in town, The Detour. Walking distance to the Castro (great bars), Hayes Valley (great bars and restaurants).