You can either fly into Los Angeles or San Diego. San Diego is about 1.5 hours away. Los Angeles is about 2.5 hours away. You will have to rent a car in order to get out to Quixote ranch.
The two hotels listed in the travel section are the closest to Quixote Ranch (Within 5-10 minutes). Your other options would be hotels in either Escondido, Temecula or Oceanside. All about 45 minutes from the ranch.
From Los Angeles (4 hours) Take I-5 south to CA76 Continue on 76 for 34.4 miles At the roundabout continue straight on 76 Turn left on RinconRanch Rd Turn right on N Mesa Dr The venue will be on the right hand side From San Diego (from airport) I-5 North to I-8 east I-8 east to CA-163 North CA-163 North to I-15 north Exit 27 via Rancho Pkwy Turn right on Rancho Pkwy turn right on East Valley Pkwy At the traffic circle take the first exit onto 76 Turn left on Rincon Ranch Rd Turn right on N Mesa Dr The venue will be on the right hand side From Harrahs Casino Turn left out of the parking lot At the traffic circle take the first exit onto CA-76 Turn left on Rincon Ranch Rd Turn right on N Mesa Dr The venue will be on the right hand side. From Pala Casino Turn right out of the parking lot onto CA-76 At the roundabout continue straight onto CA-76 Turn left on Rincon Ranch Rd Turn Right on N Mesa Dr The venue will be on the right hand side.