Patrick and Francesca fell in love because they were one in the same. When people spoke about love at first sight, it was something the two would had never thought of to be true, until first laying eyes on each other. They had a true connection from the very beginning, but worked together. They were friends and had a great friendship, until Patrick left the practice they both worked for to begin his masters at USC. When Francesca learned he was leaving, she actually asked him out, and the rest is history. They were inseparable.