Flight
If you want to make a trip of it, you could fly into San Jose International Airport or an LA-area airport, then rent a car and drive. Otherwise, the SLO airport is very quick and easy.
Travel Note
Rideshare apps like Uber and Lyft work well in the SLO area. You can also rent a car at the airport.
Hotel
~$350 per night (Friday night and Saturday night). The link should include a "celebrate" rate, but depending on when you stay, the general rate may be better.
Hotel
~$284 per night (Friday/ Saturday)
Discount Code - 14955
Hotel
~$257 a night (Friday/Saturday)
Discount Code - LPR
Hotel
~$323 a night (Friday/Saturday)
Discount Code - LSMERF