Great area to walk around downtown - filled with restaurants and shops. Good for brunch too. One of our favorite spots to eat is Cafe 4.
A fun spot in the Old City area for night life
Leslie's favorite running trail along the river
Gatlinburg and mountain areas are about an hour away - also providing several mountain hiking trails
Tennessee campus is right by downtown and fun to walk around. The new Student Union Center just opened up last year. Head to the "The Hill" where Ayers is located for a pretty view. "The strip" or Cumberland Avenue offers some restaurants and bars.