In the late 1800s, tall ships crowded the harbor as St. Marys was the southernmost point of the United States and a prime trading port for the America's. Today, the beautiful St. Marys Waterfront Park lines the river's shore and is a great place to spend some time during your stay.
Gorgeous National Park island - wild horses, old ruins, lots of walking trails, and stretches of white sand beach. You'll need a ferry reservation if you want to visit, so plan on booking early. Check their website for more details.
Jekyll Island is renowned for its landmark Historic District, termed the "Millionaire's Village" long ago, with its 240-acre site containing 33 historic structures, including the Jekyll Island Club Resort and surrounding cottages that were once home to some of America's most wealthy and prominent citizens, including the Crane family, the Pulitzers, Morgans, Vanderbilts, Rockefellers, and Goodyear clan to name but a few. Great day trip if you are coming in for a few days. Lots of beaches, Sea Turtle Sanctuary, bike trails (with rentals), hotels, etc.