While the Trevi Fountian is further of a drive (about 2 hours to 2 hours and 30 minutes) it's a beautiful sight to see if you plan to make a trip to Rome.
While the Collosseum is also about 2 hours to 2 hours and 30 minutes it's an iconic Roman amphitheater which is perfect for the history lovers (like Kory lol)!
Montepulciano is a stunning hilltop Tuscan town renowned for its wine, medieval architecture, and views of the Val d'Orcia. Activities to do in Montepulciano include wine tasting in historic underground cellars, exploring Piazza Grande, visiting the Church of San Biagio, and trying local pici pasta. Montepulciano is about 1 hour and 30 minutes away from the villa.