Flight
San Diego Airport is 25 minutes south of La Jolla. There is a trolley that runs from downtown San Diego to La Jolla/UCSD, which is proximate to (but still driving distance from) the wedding location.
Train
The Pacific Surfliner runs from Los Angeles Union Station to either Solana Beach or Old Town. The former is 25 minutes north of La Jolla, the latter is 25 minutes south. There is a trolley that runs from downtown San Diego to La Jolla/UCSD if you choose to arrive at the Old Town train station.
Hotel
Hotel
Hotel
Hotel