Justin & Josie would suggest booking an airbnb or vrbo for your stay in Cape Girardeau or Jackson. Both have a good variety of rental properties!
If you prefer a hotel here are some reccomendations.
Hotel
Best Western Plus Jackson/Cape Girardeau
3003 South Old Orchard Road, Jackson, MO 63755 (573) 987-5501
Hotel
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO 63701 (573) 334-7151
Hotel
Courtyard by Marriott Cape Girardeau Downtown
400 Broadway Street, Cape Girardeau, MO 63701 (573) 240-9420
Hotel
Hampton Inn Cape Girardeau I-55 East
207 South Mount Auburn Road, Cape Girardeau, MO 63703 (573) 334-4499
Hotel
Cape Camping & RV Park
1900 North Kingshighway Street, Cape Girardeau, MO 63701 (573) 332-8888