If you're going to fly in and rent a car. The easier route is going to be taking I-25. The scenic route is called 285 which is highly recommended if you feel safe traveling Colorado mountain passes! If you're not confident with the driving or just want to fly closer Alamosa has an airport that averages about $270 round trip.
Flight
Denver International Airport
DIA is the easiest airport to fly into. It is roughly 3.5-4 hours away.
Flight
Colorado Springs Airport
COS is a bit closer still about 3-3.5 hours north, but usually runs more expensive than flying into DIA.
Hotel
Baymont by Wyndham Monte Vista
1519 Grand Avenue, Monte Vista, CO 81144 (719) 852-3585
Hotel
Best Western Alamosa Inn
2005 Main Street, Alamosa, CO 81101 (719) 589-2567