Hotel
Train
If you're flying into O'Hare or Midway and not renting a car, you can take the Blue line from O'Hare or the Orange line from Midway. Either of those lines will take you directly to the Loop. If you're staying at the Allegro Royal Sonesta Hotel, both lines stop at Clark/Lake, just across the street from the hotel. Or you could of course take an Uber/Lyft.