Flight
If you are planning to fly in for the wedding, PDX is the closest and largest airport to Hood River, OR as well as the venue location in Trout Lake, WA. There are shuttles that run back and forth from the airport and Hood River. It is also an easy drive and takes a little under over an hour each way. Taking an Uber or taxi is very expensive, and there isn't really any Uber or taxi options in Hood River or Trout Lake.
Flight
While Portland is closer, flying into Seattle is also an option. The airport is located a little South of Seattle and is about a 4 hour drive from Hood River, OR/Trout Lake, WA. It can be a very scenic drive and there are a lot of things to see along the way. When Noah's parents came to visit us summer 2024 they flew into PDX and out of SEA. We drove together and saw Snoqualmie falls before we spent two days in Seattle.