Hotel
If you are looking to stay at a beach front hotel with spectacular views and infinity pools then I recommend The HYATT. This hotel will be an 8 minute taxi ride to the Ciudad Amurallada (Walled City) which is were the Cathedral and Reception will be located.
Flight
Please book your flight into Cartagena, Colombia from your destination. Most flights are in the AM and should arrive at Cartagena in the early afternoon. Spirit airlines has great deals traveling from Newark or Philadelphia into Cartagena.
Hotel
There are many other options to stay in Caragena! Kayak is the easiest search engine to find the perfect stay! Some close by areas are: Boca Grande, Centro Histórico, or Getsemani.