Flight
You can fly into San Francisco International Airport (SFO) or Oakland (OAK) and easily get into SF. You do not need to rent a car unless you plan to leave the city for a wine country or coastal adventure.
Hotel
We have a hotel block at the Hyatt Regency Embarcadero - https://book.passkey.com/go/jota2018 Other hotel options: Labor Day weekend is not a busy weekend in SF. Most people leave town so you should find fairly reasonable (for SF!) hotel rates around town.
Travel Note
You can catch a taxi right outside of either airport. We would recommend calling an Uber once you have your bags as they have a negotiated rate and it is less expensive. Uber will pick you up on the Departures level (above baggage claim) at SFO. It's a flat rate of about $30 to anywhere in SF.
House Or Rental
Airbnb is a great option in SF