Flight
This is the nearest major airport - it is about a 40 minute drive to Tybee Island. Main options for transportation include Uber or Taxi.
Hotel
Beachfront charm with walkable access to the pier and restaurants
Hotel
Cozy, local feel. Good for if you're looking for something with personality.
Hotel
If you prefer to stay in Savannah (more nightlife, dining, and city feels), you can always drive/ride to Tybee for the day. The drive is short, and you'll get that classic southern charm overnight. Look for hotels near the Historic District, which will give you a great base to explore Savannah when you're not on the beach.