Flight
You will want to fly from your home location to Athens (ATH -Athens International Airport). From there you will need to take a small plane or Ferry to Santorini.
Hotel
Santorini is a relatively small island, and hotel blocks aren't a thing as almost all hotels are local and boutique! You can't go wrong and there are so many amazing options from local hotels, to house/villa rentals all over the island. However, here are a list of some towns and hotels to consider :) Akrotiri (Town where the wedding will be - Venue is CAVO VENTUS LUXURY VILLA ) https://www.calderaview-santorini.com https://www.santoriniprincess-suites.com https://www.melidoniasuites.com https://thefishermanshouse.com https://www.ambassadorhotelsantorini.com Fira (main town, close to bars / restaurants / shops) https://www.whiteark.gr https://kamares-apartments.gr https://www.enigmasantorini.com https://www.santoriniwineryhotel.com Imerovigli - Firostefani (two villages right next to Fira that have mainly hotels and are more quiet that Fira) https://www.remezzo-santorini.com https://www.thevasilicos.com https://www.altavistasuites.com https://hotelgalini.gr
Rental Car
Santorini does not have Uber or Lyfts. Taxis are available, but most people get around on ATV/4 Wheelers! This is what we did in the past, there are literally rental areas everywhere for these :) Car rentals do exist at the airports too if thats more your thing!