Pepin is on the WI side of the Mississippi. The hotel listed is located on the opposite side of the river in MN. If you don’t want to book a hotel room, there are plenty of air bnb options in Pepin and Wabasha
Hotel
AmericInn by Wyndham Wabasha
150 Commerce Street, Wabasha, MN 55981
This is going to be the closest big hotel in the area. This is about 10 minutes away from the wedding venue.
Flight
Minneapolis- Saint Paul International Airport
This is the largest airport that would also be the closest to Pepin. This is about 1 hour and 20 minutes from Pepin, WI.