Hotel
Watch the Baltimore Running Festival go on Saturday morning by while you sip a mimosa at Topside! Revival is also walking distance from all Mt. Vernon has to offer, including The Walters, The Peabody Library, and plenty of coffee shops and restaurants.
Hotel
Also in Mount Vernon, we love Ulysses for it's funky style, and for the cocktails at Bloom's and Ash Bar! Bonus points awarded for being across the street from a late-night food spot (and a block and a half from Kelly's old apartment).
Train
If you're coming from another east coast city, taking the Amtrak to Baltimore's Penn Station is a great option! The station is walkable to hotels in the Mt. Vernon neighborhood, as well as the light rail and other public transit.
Flight
While you could technically fly into a DC airport (Reagan or Dulles), BWI is going to be the easiest by far. Rental cars are available at the airport, as well as the light rail and MARC trains that connect directly into Baltimore. Uber and Lyft are usually available as well!